التفاصيل البيبلوغرافية
| العنوان: |
INFLUENCE OF HYPOXIC SWIMMING EXERCISE ON OXIDATIVE STRESS AND CELL DAMAGE. |
| المؤلفون: |
Ahmed Hussein, Hazem Hussein Salem |
| المصدر: |
International Journal of Pharmacology & Biological Sciences; Aug2011, Vol. 5 Issue 2, p39-44, 6p |
| مصطلحات موضوعية: |
EXERCISE, OXIDATIVE stress, BODY fluids, TISSUES, SWIMMING therapy |
| مستخلص: |
Acute hypoxic exercise can induce a state of oxidative stress affecting many tissues and body fluids. Many coaches believe hypoxic swimming training resembles altitude training. The purpose of this study was to compare the oxidative stress response to hypoxic swimming exercise testing, and to determine the impact of exercise training effect after 24 hours. Methods of study were used for fourteen swimmers (National Olympic team) exercised for hypoxic swimming (Maglisho). Blood samples were collected at rest, after exercise 0 time and after 24 hours following a protocol of ischemia-reperfusion, and analyzed for malondialdehyde (MDA). Urine samples from the first morning was collected, one hour after exercise and 24 hours after exercise, were analyzed for 8-hydroxydeoxyguanosine (8-OHdG). Results revealed significant increase (P< 0.05) in plasma MDA levels and urine 8-OHdG after exercise, returned to near base line after 24 hours. It is concluded that hypoxia generates more DNA strand breaks and oxidative DNA damage in swimmers may due to insufficient antioxidant protection, cleared within 24 hours to the base concentrations. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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