كتاب
Central Nervous System Rosai–Dorfman Disease.
| العنوان: | Central Nervous System Rosai–Dorfman Disease. |
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| المؤلفون: | Raslan, Osama, Ketonen, Leena M., Fuller, Gregory N., Schellingerhout, Dawid |
| المصدر: | Methods of Cancer Diagnosis, Therapy & Prognosis; 2010, p365-373, 9p |
| مستخلص: | In 1969, Rosai and Dorfman described the triad of massive cervical lymphadenopathy, expanded lymph node sinuses and characteristic histiocytes showing ˵emperipolesis″ as a new, rare, idiopathic, nonneoplastic, lymphoproliferative disorder known as Rosai Dorfman Disease (RDD) or `sinus histiocytosis with massive lymphadenopathy (SHML) (Rosai and Dorfman 1969). Since then, over 750 cases have been reported in the literature (Hargett and Bassett 2005). Typically, RDD is characterized by bilateral painless cervical lymphadenopathy with fever, leukocytosis, increased erythrocyte sedimentation rate and hypergammaglobulinaemia (Chopra et al. 2006). However, in approximately 40% of cases, extranodal lesions in the skin, upper respiratory tract, orbit, testicle, soft tissue, kidney, thyroid, small bowel, breast, and bone can be found (Ruggiero et al. 2006). [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: | Complementary Index |
Full Text Finder | ردمك: | 9789048186648 |
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| DOI: | 10.1007/978-90-481-8665-5_28 |