التفاصيل البيبلوغرافية
| العنوان: |
SENSITIVE-SENSORIAL DISORDERS IN PARKINSON'S DISEASE. |
| المؤلفون: |
Cuibus, Liliana, Pereanu, M. |
| المصدر: |
Acta Medica Transilvanica; sep2012, Vol. 17 Issue 3, p188-191, 4p |
| مصطلحات موضوعية: |
BASAL ganglia, PARKINSON'S disease, DOPAMINERGIC mechanisms, SYMPATHETIC nervous system, SEROTONINERGIC mechanisms, PATHOLOGICAL physiology, PAIN |
| Abstract (English): |
The incapacity of basal ganglions to modulate the sensory information due to impaired serotonergic pathways is common in over 50% of the patients with Parkinson's disease. Ipsilateral rheumatic pain at first extremity affected by resting tremor is the most common. Dopaminergic denervation can induce pain hypersensitivity at central level through the stimuli that leave the basal ganglions and go up to the thalamus. The pathophysiology of the above disorders is less known. [ABSTRACT FROM AUTHOR] |
| Abstract (Romanian): |
Incapacitatea ganglionilor bazali de a modula informaţia senzorială datorită alterării căilor serotoninergice este frecventă la peste 50% dintre pacienţii cu boala Parkinson. Durerea reumatică ipsilaterală la extremitatea întâi afectată de tremor de repaus este cea mai frecventă. Denervarea dopaminergică poate induce o hipersenzitivitate la durere la nivel central prin stimuli care pleacă de la ganglionii bazali la talamus. Fiziopatologia tulburărilor de mai sus este puţin cunoscută. [ABSTRACT FROM AUTHOR] |
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