دورية أكاديمية

Dilated and Unreactive Pupils and Burst-Suppression on Electroencephalography due to Buproprion Overdose.

التفاصيل البيبلوغرافية
العنوان: Dilated and Unreactive Pupils and Burst-Suppression on Electroencephalography due to Buproprion Overdose.
المؤلفون: Mundi, Jyoti Pathria, Betancourt, Jaime, Ezziddin, Omar, Tremayne, Brandie, Majic, Tamara, Mosenifar, Zab
المصدر: Journal of Intensive Care Medicine; Nov2012, Vol. 27 Issue 6, p384-388, 5p
مصطلحات موضوعية: DRUG overdose, ELECTROENCEPHALOGRAPHY, BUPROPION
مستخلص: Burst-suppression pattern on electroencephalography (EEG) occurs upon dissociation of the cortex from underlying brain structures. Unless the pattern is a physiologic consequence of administered sedatives, this electroencephalographic pattern is indicative of a poor neurologic outcome and high mortality. We report a case of a 29-year-old female thought to be brain dead based on initial physical examination and EEG findings of burst-suppression, who was later found to have supratherapeutic serum levels of bupropion. This is the second documented case of burst-suppression pattern on EEG in a patient who overdosed on bupropion. We propose that burst-suppression in the setting of bupropion toxicity may revert with drug clearance. [ABSTRACT FROM PUBLISHER]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:08850666
DOI:10.1177/0885066611429661