التفاصيل البيبلوغرافية
| العنوان: |
Effects of 17β-Estradiol, Progesterone and Tamoxifen on in vitro Proliferation of Human Pituitary Adenomas: Correlation with Specific Cellular Receptors. |
| المؤلفون: |
Caronti, Brunella, Palladini, Guido, Bevilacqua, Maria Gabriella, Petrangeli, Elisa, Fraioli, Bernardo, Cantore, Giampaolo, Tamburrano, Guido, Carapella, Carmine Maria, Jaffrain-Rea, Marie Lise |
| المصدر: |
Tumor Biology (Springer Science & Business Media B.V.); 1993, Vol. 14 Issue 1, p59-68, 10p |
| مستخلص: |
Six human pituitary adenoma cultures, characterized for estrogen and progesterone (Pg) receptors, were treated with 17β-estradiol (17β-E2), Pg and tamoxifen (TAM) at different concentrations, alone and in combination, for 2, 4 and 8 days. Cell proliferation data showed in most cases a stimulating effect of 17β-E2 and an inhibitory effect of Pg on cell growth, which appeared to be correlated with specific receptor expression, but independent of pituitary cell hormone content. A marked inhibitory effect of TAM on cell proliferation was present in all cases, but, on the contrary, was independent of estrogen receptor expression. Copyright © 1993 S. Karger AG, Basel [ABSTRACT FROM AUTHOR] |
|
Copyright of Tumor Biology (Springer Science & Business Media B.V.) is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
