التفاصيل البيبلوغرافية
| العنوان: |
Meta-analysis of prospective trials determining the short- and mid-term effect of elective open and endovascular repair of abdominal aortic aneurysms on quality of life. |
| المؤلفون: |
Coughlin, P. A., Jackson, D., White, A. D., Bailey, M. A., Farrow, C., Scott, D. J. A., Howell, S. J. |
| المصدر: |
British Journal of Surgery; Apr2013, Vol. 100 Issue 4, p448-455, 8p |
| مصطلحات موضوعية: |
META-analysis, LONGITUDINAL method, ENDOVASCULAR surgery, AORTIC aneurysms, ABDOMINAL aorta, ABDOMINAL aortic aneurysms, QUALITY of life, HEALTH outcome assessment |
| مستخلص: |
Background: Repair of an abdominal aortic aneurysm (AAA) is undertaken to prevent rupture. Intervention is by either open repair (OR) or a more minimally invasive endovascular repair (EVAR). Quality-of-life (QoL) analysis is an important health outcome and a number of single studies have assessed QoL following OR and EVAR. This was a meta-analysis of published studies to assess the effect of an intervention on QoL in patients with an AAA. Methods: A systematic literature search was undertaken for studies prospectively reporting QoL analysis in patients with an AAA undergoing elective intervention. A multivariable meta-analysis model was developed in which the outcomes were mean changes in QoL scores over time, both for all AAA repairs (OR and EVAR) and comparing OR with EVAR. Results: Data were collated from 16 studies (14 OR, 12 EVAR). The results suggested that treating an AAA had an effect on patient-reported QoL, evident from the statistically significant changes predominantly in domains assessing physical ability and pain. QoL was affected most within the first 3 months after any form of intervention, and was more pronounced following OR. Furthermore, a deterioration in the Physical Component Summary score following an AAA repair (either OR or EVAR) was evident at 12 months after intervention. Conclusion: Treating an AAA deleteriously affects patient-reported QoL over the first year following intervention. Copyright © 2012 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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