التفاصيل البيبلوغرافية
العنوان: |
MOLECULAR ANALYSIS AND PATHOLOGY OF A SECOND PEDIATRIC HIV-ASSOCIATED BURKITT LYMPHOMA. |
المؤلفون: |
Cabalo, Eve, Wilkinson, Robert, Lu, Nu T., Shimizu, Sheri, Melish, Marian, McClain, Kenneth L., Jenson, Hal B., Shiramizu, Bruce |
المصدر: |
Pediatric Pathology & Molecular Medicine; Nov2002, Vol. 21 Issue 6, p525-530, 6p |
مصطلحات موضوعية: |
BURKITT'S lymphoma, PEDIATRIC pathology |
مستخلص: |
Diagnosis of a second HIV-associated non-Hodgkin lymphoma (HIV-NHL) is rare, but additional cases may occur as aggressive therapy for both HIV and NHL improves. An 11-year-old presented with a second primary HIV-NHL following remission for 9 years. Analysis of the tumor demonstrated presence of EBV and HIV with absence of CMV, HHV-8, and HHV-6. Although microscopic disease was present only in CSF, analysis of peripheral blood and bone marrow by PCR was positive. The patient underwent a stem cell transplant, but within 3 months, his disease recurred. Analysis for residual disease and viruses in similar cases may provide information in understanding pediatric HIV-NHL. [ABSTRACT FROM AUTHOR] |
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قاعدة البيانات: |
Complementary Index |