التفاصيل البيبلوغرافية
| العنوان: |
Sex Differences in Peripheral Arterial Disease: Leg Symptoms and Physical Functioning. |
| المؤلفون: |
McDermott, Mary McGrae, Greenland, Philip, Liu, Kiang, Criqui, Michael H., Guralnik, Jack M., Celic, Lillian, Chan, Cheeling |
| المصدر: |
Journal of the American Geriatrics Society; Feb2003, Vol. 51 Issue 2, p222-228, 7p, 2 Charts |
| مصطلحات موضوعية: |
ARTERIAL occlusions, ARTERIAL diseases |
| مستخلص: |
OBJECTIVES: LTo compare lower extremity functioning and leg symptoms between women and men with peripheral arterial disease (PAD). DESIGN: Cross-sectional. SETTING: Three Chicago-area medical centers. PARTICIPANTS: One hundred eighty-seven women and 273 men with PAD identified consecutively in patients in the noninvasive vascular laboratories and a general medicine practice at the three medical centers. MEASUREMENTS: Walking speed, 6-minute walk, accelerometer-measured 7-day physical activity, and a summary performance score. The summary performance score combines data on walking velocity, time for five repeated chair rises, and standing balance to achieve a score on a 0 to 12 scale (12 = best). RESULTS: Women with PAD were older and had a lower prevalence of prior leg revascularization, a higher prevalence of spinal stenosis, and a lower prevalence of other cardiovascular disease than men with PAD. Mean ankle brachial index (ABI) values ± standard deviation were similar in women and men with PAD (0.64 ± 0.15 vs 0.66 ± 0.14, P = .15). Women with PAD were significantly more likely than men with PAD to have exertional leg pain that sometimes begins at rest (27.8% vs 13.2%, P < .001). Women with PAD had slower walking speed (0.81 vs 0.92 m/s, P < .001), shorter 6-minute walk distance (1,047 vs 1,182 feet, P < .001), and a poorer summary performance score (8.9 vs 9.8, P < .001) than men with PAD, adjusting for age, race, height, comorbid disease, and leg symptoms. After adjusting for leg strength, sex differences in 6-minute walk performance and summary performance score were attenuated modestly (1,089 vs 1,177 feet for 6-minute walk, P = .022 and 9.2 vs 9.8 for summary performance score, P = .027). CONCLUSION: Women with PAD had a higher prevalence of leg pain on exertion and rest, poorer functioning, and greater walking impairment from leg symptoms than men with PAD. A higher prevalence of spinal stenosis in women may explain the observed sex... [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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