التفاصيل البيبلوغرافية
العنوان: |
Is Your System Calibrated? MRI Gradient System Calibration for Pre-Clinical, High-Resolution Imaging. |
المؤلفون: |
O’Callaghan, James, Wells, Jack, Richardson, Simon, Holmes, Holly, Yu, Yichao, Walker-Samuel, Simon, Siow, Bernard, Lythgoe, Mark F. |
المصدر: |
PLoS ONE; May2014, Vol. 9 Issue 5, p1-9, 9p |
مصطلحات موضوعية: |
MAGNETIC resonance imaging, MEDICAL imaging systems, HIGH resolution imaging, SMALL animal culture, CALIBRATION, CLINICAL trials, STANDARDS |
مستخلص: |
High-field, pre-clinical MRI systems are widely used to characterise tissue structure and volume in small animals, using high resolution imaging. Both applications rely heavily on the consistent, accurate calibration of imaging gradients, yet such calibrations are typically only performed during maintenance sessions by equipment manufacturers, and potentially with acceptance limits that are inadequate for phenotyping. To overcome this difficulty, we present a protocol for gradient calibration quality assurance testing, based on a 3D-printed, open source, structural phantom that can be customised to the dimensions of individual scanners and RF coils. In trials on a 9.4 T system, the gradient scaling errors were reduced by an order of magnitude, and displacements of greater than 100 µm, caused by gradient non-linearity, were corrected using a post-processing technique. The step-by-step protocol can be integrated into routine pre-clinical MRI quality assurance to measure and correct for these errors. We suggest that this type of quality assurance is essential for robust pre-clinical MRI experiments that rely on accurate imaging gradients, including small animal phenotyping and diffusion MR. [ABSTRACT FROM AUTHOR] |
|
Copyright of PLoS ONE is the property of Public Library of Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
قاعدة البيانات: |
Complementary Index |