التفاصيل البيبلوغرافية
| العنوان: |
Marijuana use differentially affects cannabinoid receptor expression in early gestational human endometrium and placenta. |
| المؤلفون: |
Neradugomma, Naveen K., Drafton, Kaitlyn, O'Day, Diana R., Liao, Michael Z., Han, Lyrialle W., Glass, Ian A., Mao, Qingcheng, O'Day, Diana R |
| المصدر: |
Placenta; Jun2018, Vol. 66, p36-39, 4p |
| مصطلحات موضوعية: |
RNA metabolism, CELL receptors, CELLULAR signal transduction, COMPARATIVE studies, ALCOHOL drinking, ENDOMETRIUM, RESEARCH methodology, MEDICAL cooperation, PLACENTA, FIRST trimester of pregnancy, SECOND trimester of pregnancy, RESEARCH, RESEARCH funding, RNA, SMOKING, EVALUATION research, CASE-control method |
| مستخلص: |
Marijuana is one of the most abused drugs among pregnant women leading to maternal and fetal abnormalities. Cannabinoids are the active ingredients of marijuana, which interact with cannabinoid receptors such as CNR1 and CNR2 to activate cellular signaling pathways. Human endometrium and placenta are known to express CNR1 and CNR2 and can respond to cannabinoid signaling. In this study, we show that marijuana use significantly increases mRNA or protein expression of CNR1 and CNR2 in human endometrium from the first and early second trimester pregnancies, with minor effects on placental expression of CNRs. [ABSTRACT FROM AUTHOR] |
|
Copyright of Placenta is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Supplemental Index |
Full Text via ClinicalKey 
Full Text Finder