التفاصيل البيبلوغرافية
| العنوان: |
The Effect of the Neurotransmitter Dopamine, Lead Acetate, L-NAME, and Verapamil on the Metabolic Pathway in the Longitudinal Smooth Muscle. |
| المؤلفون: |
Ferizi, Rrahman, Shabani, Nora, Shabani, Ragip, Haliti, Naim |
| المصدر: |
Journal of International Dental & Medical Research; 2020, Vol. 13 Issue 2, p758-768, 11p |
| مصطلحات موضوعية: |
SMOOTH muscle, VERAPAMIL, LEGHORN chicken, CALCIUM ions, ACETATES |
| مستخلص: |
The purpose of this study was evaluating the effect of dopamine neurotransmitter in the constrictive response of Ileum longitudinal smooth muscle (ILSM) in White Leghorn chickens (Gallus gallus domesticus) in the relation of lead acetate, verapamil (as a calcium ion blocker). This study also includes the role of epithelium and involvement of dopamine with and without nitric oxide synthesis inhibitor L-NAME (NOS blocker) that significantly increase the effect of ileum longitudinal smooth muscle (ILSM). While the application of lead acetate in different doses with dopamine has shown an increasing effect on the ileum longitudinal smooth muscle (ILSM) under "in vitro" conditions dependent on different concentration. Also, this research reflected the effect of verapamil as a blocker of the Ca2+ ionic channels that decreased the contraction of the ileum longitudinal smooth muscle (ILSM) in the application with L-NAME and lead acetate. [ABSTRACT FROM AUTHOR] |
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