التفاصيل البيبلوغرافية
| العنوان: |
Successful outcome after a single endoscopic fecal microbiota transplantation in a Shiba dog with non-responsive enteropathy during the treatment with chlorambucil. |
| المؤلفون: |
Koji SUGITA, Ayaka SHIMA, Kaho TAKAHASHI, Yasuyoshi MATSUDA, Masaki MIYAJIMA, Marin HIROKAWA, Hirotaka KONDO, Junpei KIMURA, Genki ISHIHARA, Keitaro OHMORI |
| المصدر: |
Journal of Veterinary Medical Science; 2021, Vol. 83 Issue 6, p984-989, 6p |
| مصطلحات موضوعية: |
FECAL microbiota transplantation, INTESTINAL diseases, CHLORAMBUCIL, DOG breeding, PROGNOSIS, DOGS, DOG breeds |
| مستخلص: |
A 7-year 6-month-old, castrated male Shiba dog presented with a 1-month history of lethargy, anorexia, vomiting, and frequent watery diarrhea. Weight loss, hypoalbuminemia, anemia, and leukocytosis were detected at the first visit. The dog was diagnosed with nonresponsive enteropathy (NRE) based on clinical and histopathological examinations. Since the dog did not respond to the immunosuppressive drugs, fecal microbiota transplantation (FMT) was performed during the treatment with chlorambucil. A single endoscopic FMT into the cecum and colon drastically recovered clinical signs and clinicopathological abnormalities and corrected dysbiosis in the dog. No recurrence or adverse events were observed. The present case report suggests that FMT, possibly together with chlorambucil, might be a treatment option for NRE in Shiba dogs that have poorer prognosis compared with other dog breeds. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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