التفاصيل البيبلوغرافية
| العنوان: |
Association of Pre-Operative Vitamin D Levels and Severity of Fracture among Orthopedic Trauma Patients in A Single, Tertiary-Level Hospital. |
| المؤلفون: |
Mendoza, Christian Julius P., Ver, Mikhail Lew Perez, Tabberrah, Andrew Gabriel Jacinto, Ver, Mario Ratio |
| المصدر: |
Journal of Orthopaedics, Trauma & Rehabilitation; Jan-Dec2021, Vol. 28, p1-8, 8p |
| مستخلص: |
Background/Purpose: The high prevalence of hypovitaminosis D among trauma patients have been related to risk of fractures, falls, non-union and poor operative outcomes. There is limited evidence that ties up Vitamin D levels with fracture severity. The objective of this study is to determine the association of pre-operative Vitamin D levels and fracture severity. Methods: This was a retrospective, cross-sectional study of patients with extremity fractures classified according to the AO Trauma classification system with baseline pre-operative vitamin D levels. The association between vitamin D levels and fracture severity of surgically treated trauma patients were analyzed. Sub-group analysis was performed on patients without osteoporosis and those patients who suffered from low-energy trauma. Results: Ninety-six (96) patients were included. Those with severe fractures (AO -C fractures, 31B1.3/B2.3 and 31A3) were associated with lower Vitamin D levels (µ = 17.87 µg/mL) (p < 0.001). There was a strong, positive significant correlation (rs (4) =.426, p = < 0.001) between hypovitaminosis D and increasing fracture severity. This significant association of hypovitaminosis D with worse fracture patterns remains in the patient sub-group without osteoporosis (p = 0.030), and in those who sustained low-mechanism injuries (- p- < 0.001). Conclusion: We present initial evidence that low pre-operative Vitamin D level is associated with increasing fracture severity at the time of injury. Early detection, surveillance and management of low vitamin D levels can lead to drastic changes in the holistic approach to fracture prevention and treatment. [ABSTRACT FROM AUTHOR] |
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