Discovery of N-Trisubstituted Pyrimidine Derivatives as Type I RET and RET Gatekeeper Mutant Inhibitors with a Novel Kinase Binding Pose.

التفاصيل البيبلوغرافية
العنوان:	Discovery of N-Trisubstituted Pyrimidine Derivatives as Type I RET and RET Gatekeeper Mutant Inhibitors with a Novel Kinase Binding Pose.
المؤلفون:	Lingtian Zhang, Moccia, Marialuisa, Briggs, David C., Bharate, Jaideep B., Lakkaniga, Naga Rajiv, Knowles, Phillip, Wei Yan, Tran, Phuc, Kharbanda, Anupreet, Xiuqi Wang, Yuet-Kin Leung, Frett, Brendan, Santoro, Massimo, McDonald, Neil Q., Carlomagno, Francesca, Hong-yu Li
المصدر:	Journal of Medicinal Chemistry; 1/27/2022, Vol. 65 Issue 2, p1536-1551, 16p
قاعدة البيانات:	Supplemental Index

الوصف
تدمد:	00222623
DOI:	10.1021/acs.jmedchem.1c01280