التفاصيل البيبلوغرافية
| العنوان: |
PROGNOSTIC FACTORS FOR OROPHARYNGEAL SQUAMOUS CELL CARCINOMA: RETROSPECTIVE COHORT. |
| المؤلفون: |
De Figueiredo Pires, Hévila, De França, Glória Maria, Da Silva, Weslay Rodrigues, Medeiros, Cristianne Kalinne Santos, Oliveira, Marvin Felipe, Felipe, Joaquim, Galvão, Hébel Cavalcanti |
| المصدر: |
Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology; Sep2022, Vol. 134 Issue 3, pe202-e202, 1p |
| مستخلص: |
Squamous cell carcinoma is the most common histologic subtype of cancer in the oropharynx. The present research aimed to evaluate the 5-year overall survival and prognostic factors for oropharyngeal squamous cell carcinoma. The study population was a hospital-based cohort consisting of patients diagnosed with oropharyngeal cancer (2008-2018) who underwent surgery and/or adjuvant therapy (radio- and/or chemotherapy). A total of 253 patients with oropharyngeal squamous cell carcinoma were analyzed. Smoking and alcohol consumption were found in 88.0% and 84.2% of the sample, respectively. The combination of radiotherapy and chemotherapy was the treatment modality in 42.7% of the sample. There were 143 deaths, the mean survival was 11.55 ± 9.69 months, and the 5-year overall survival rate was 1.1%. Overall survival was lower for clinical stage III/IV (P <.001) and human papillomavirus P16 status (P =.019) and for an interval >4 weeks between diagnosis and the beginning of treatment (P <.007). Tumor stage III/IV and an interval longer than 4 weeks between diagnosis and the beginning of treatment were significant prognostic factors associated with lower overall survival. [ABSTRACT FROM AUTHOR] |
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