التفاصيل البيبلوغرافية
| العنوان: |
Comparison of serum albumin level and lactate for predicting preterm morbidities and mortality. |
| Alternate Title: |
Preterm morbiditeleri ve mortalitesinin tahmininde serum albümini ile laktat düzeyinin karşılaştırılması. (Turkish) |
| المؤلفون: |
Elataş, Aygül, Gülaşı, Selvi, Mert, M. Kurthan, Çekinmez, Eren K., Tolunay, Orkun |
| المصدر: |
Cukurova Medical Journal / Çukurova Üniversitesi Tip Fakültesi Dergisi; 2023, Vol. 48 Issue 1, p127-135, 9p |
| مصطلحات موضوعية: |
SERUM albumin, HYPERLACTATEMIA, LACTATES, LACTATION, PREMATURE infants, NEONATAL mortality |
| Abstract (English): |
Purpose: We aimed to comparison of serum albumin and lactate level for predicting neonatal morbidities and mortality in preterm infants < 32 weeks of gestation. Materials and Methods: The medical records of babies were retrospectively analyzed. Patients were divided into three groups; plasma albumin levels ≤ 2.5 g/dL were defined as Group 1, 2.6-3 g/dL as Group 2 and ≥ 3 g/dL as Group 3. The babies < 28 weeks of gestation were analysed as a subgroup. Results: 300 infants with mean gestational age of 28.7 ± 2.4 weeks and mean birth weights 1240 ± 405 grams were included. In predicting mortality; the sensitivity of the albumin level within the first three days was 74.4% and the specificity was 73.2% (cut-off < 2.9 g/dL), the sensitivity of the lowest albumin level was 90.7% and the specificity was 70.1% (cut-off < 2.65 g/dL), the sensitivity of the lactate level was 67.4% and the specificity was 63.3% (cut off > 3.1 mmol/L). Analysis of < 28 weeks babies; the sensitivity of lowest albumin level was 80% and the specifity was 66.7% (cut-off < 2.45 g/dL) and the sensitivity of the albumin level within the first three days was 74.3% and the specificity was 72.6% (cut-off < 2.8 g/dL), and the sensitivity of lactate was 74.3% and the specifity was 64.2% (cut-off > 3.1mmol/L). Conclusion: Low serum albumin level appears to be more specific and sensitive than lactate in predicting mortality and may be considered to be added to mortality prediction scores. [ABSTRACT FROM AUTHOR] |
| Abstract (Turkish): |
Amaç: 32 haftadan küçük preterm bebeklerde neonatal morbiditeleri ve mortaliteyi öngörmede serum albumin ve laktat düzeylerini karşılaştırmayı amaçladık. Gereç ve Yöntem: Bebeklerin tıbbi kayıtları retrospektif olarak incelendi. Hastalar üç gruba ayrıldı; plazma albümin düzeyi ≤ 2.5 g/dL olanlar Grup 1, 2.6-3 g/dL olanlar Grup 2 ve ≥ 3 g/dL olanlar Grup 3 olarak tanımlandı. < 28 gebelik haftası olan bebekler alt grup olarak analiz edildi. Bulgular: Ortalama gebelik yaşı 28.7 ± 2.4 hafta ve ortalama doğum ağırlığı 1240 ± 405 gram olan 300 bebek dahil edildi. Mortaliteyi öngörmede; ilk üç gün içindeki albümin düzeyi duyarlılığı %74.4 ve özgüllüğü %73.2 (cutoff < 2.9 g/dL), en düşük albümin seviyesinin duyarlılığı %90.7 ve özgüllüğü %70.1 (cut-off < 2.65 g/dL), laktat seviyesinin duyarlılığı %67.4 ve özgüllüğü %63.3 (cut-off > 3.1 mmol/L) idi. < 28 hafta bebeklerin analizinde; en düşük albümin seviyesinin duyarlılığı %80 ve özgüllüğü %66.7 (cut-off < 2.45 g/dL), ilk üç gün içindeki albümin seviyesinin duyarlılığı %74.3 ve özgüllüğü %72.6 (cut-off < 2.8 g/dL), laktatın duyarlılığı %74.3 ve özgüllüğü %64.2 (cut-off > 3.1 mmol/L) idi. Sonuç: Düşük serum albumin düzeyi mortaliteyi öngörmede laktata göre daha özgül ve duyarlı görünmektedir ve mortalite tahmin skorlarına eklenmesi düşünülebilir. [ABSTRACT FROM AUTHOR] |
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