التفاصيل البيبلوغرافية
| العنوان: |
Analgesic efficacy of local anesthesia during thyroid fine-needle aspiration biopsy: A PRISMA-compliant systematic review and meta-analysis of randomized controlled trials. |
| المؤلفون: |
Albazee, Ebraheem, Alhubail, Rawan Jamal, Alsakka, Mahmoud Abdelaziz, Al Sadder, Khaled Ahmad, Hammoud, Sabri Moussa, Alshakhri, Abdulrazzaq |
| المصدر: |
Egyptian Journal of Anaesthesia; Dec2023, Vol. 39 Issue 1, p335-341, 7p |
| مستخلص: |
Aim: The objective of this study is to evaluate the analgesic efficacy of local anesthetic (LA) agents on pain severity among patients undergoing thyroid fine needle aspiration biopsy (FNAB). Design: A systematic review and meta-analysis of randomized controlled trials (RCTs). Methods: Digital databases, including PubMed, Scopus, Cochrane, Web of Science, and Google Scholar, were systematically screened from inception till December 2022. The Cochrane risk of bias tool (ROB 2) was used to evaluate the quality of each RCT. The primary outcome (pain severity) was gathered as a mean difference (MD) with a 95% confidence interval (Cl), under the random-effect model. Results: Overall, 444 patients were enrolled in five RCTs. Regarding pain severity via the visual analogue scale (VAS) assessment tool, the overall effect size showed no substantial difference between LA and control groups (n = 4 RCTs, MD = -8.45, 95% CI [-27.41, 10.52], p = 0.38). Regarding pain severity via the numerical rating scale (NRS) assessment tool, the overall effect size showed no substantial difference between LA and control groups (n = 3 RCTs, MD = -0.85, 95% CI [-3.14, 1.45], p = 0.47). Conclusion: We have found that the pain levels between the LA and control-receiving groups were comparable. Hence, we concluded that LA before FNAB provides no benefit, especially for one needle puncture and sampling. [ABSTRACT FROM AUTHOR] |
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