التفاصيل البيبلوغرافية
| العنوان: |
New Findings from University of Pennsylvania Update Understanding of Yersinia (A Tnf-il-1 Circuit Controls yersinia Within Intestinal Pyogranulomas). |
| المصدر: |
Health & Medicine Week; 4/12/2024, p3314-3314, 1p |
| مستخلص: |
New research from the University of Pennsylvania provides new insights into the role of tumor necrosis factor (TNF) and interleukin-1 (IL-1) in controlling Yersinia infection in the intestines. The study found that TNF signaling in monocytes is necessary for containing the bacteria, and that monocyte-derived IL-1 signals to non-hematopoietic cells to enable control of the infection. This collaborative inflammatory circuit restricts intestinal Yersinia infection. The findings contribute to a better understanding of the immune response to Yersinia and may have implications for the development of new treatments. [Extracted from the article] |
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| قاعدة البيانات: |
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