التفاصيل البيبلوغرافية
| العنوان: |
In situ detection of enzymatic activities by the bioorthogonal reaction-coupled assay using a dialkoxysilylated fluorogenic probe. |
| المؤلفون: |
Daisuke Sato, Yuya Matsuo, Yuki Nishime, Shohei Uchinomiya, Akio Ojida |
| المصدر: |
Chemistry Letters; Mar2024, Vol. 53 Issue 3, p1-5, 5p |
| مستخلص: |
Fluorescent probes are indispensable tools for detection of enzymatic activities. However, detection of enzymes with high substrate specificity with substrate-based fluorescent probes is still challenging, due to their relatively large molecular size. We report herein enzyme assays coupled with a bioorthogonal fluoride ion-induced desilylation of fluorogenic probe. This sensing system is useful for in situ detection of enzyme reactions with high substrate specificity. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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