دورية أكاديمية

COMBINED CENTRAL RETINAL VASCULAR OCCLUSION AS THE PRESENTING FEATURE IN β-THALASSEMIA WITH IRON DEFICIENCY ANEMIA.

التفاصيل البيبلوغرافية
العنوان: COMBINED CENTRAL RETINAL VASCULAR OCCLUSION AS THE PRESENTING FEATURE IN β-THALASSEMIA WITH IRON DEFICIENCY ANEMIA.
المؤلفون: Huangdong Li, Chengyi Liu, Huang, Amy Michelle, Jingyu Zhang, Ruiming Yang, Xiangyin Sha, Zhiping Liu
المصدر: Retinal Cases & Brief Reports; May2024, Vol. 18 Issue 3, p393-395, 3p
مستخلص: Purpose: To report a case of b-thalassemia trait with iron deficiency anemia presenting as a combined central retinal vein and artery occlusion. Methods: Case report. A 22-year-old woman presented with sudden-onset blurry vision in the left eye of 3-day duration. Results: Best-corrected visual acuity was 20/20 and 20/1000 in right and left eyes, respectively. Fundus examination of the left eye revealed optic disk edema, macular whitening with a cherry-red spot, markedly dilated and tortuous retinal veins, and hemorrhages both around the disk and extending into the macula and the periphery. Fundus fluorescein angiography showed delayed filling of retinal vasculature, dilated and tortuous retinal veins, and blocked fluorescence around and beyond the optic disk. Optical coherence tomography scan at presentation showed hyperreflective inner retinal layers with neurosensory detachment. Optical coherence tomography angiography showed that the vessel densities of superficial and deep capillary plexus were remarkably reduced. A diagnosis of b-thalassemia trait combined with iron deficiency anemia was made after hematologic workup. The patient was treated with a course of oral iron supplements, vasodilator (compound Xueshuantong), inhalation of a mixture of 5% carbon dioxide and 95% oxygen, and a nutritional agent (compound anisoine). Six months later, her visual acuity improved to 20/60 in the left eye with complete resolution of all clinical signs. Conclusion: Combined central retinal vein and artery occlusion is a rare emergency leading to acute vision loss and can manifest in patients with b-thalassemia trait with iron deficiency anemia. Prompt diagnosis and early management is important to treat underlying systemic disorders and to prevent occurrence of a similar episode in fellow eye. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Supplemental Index
الوصف
تدمد:19351089
DOI:10.1097/icb.0000000000001392