Synthesis, Antimalarial Activity, and Preclinical Pharmacology of a Novel Series of 4′-Fluoro and 4′-Chloro Analogues of Amodiaquine. Identification of a Suitable “Back-Up” Compound for N-tert-Butyl Isoquine.

التفاصيل البيبلوغرافية
العنوان:	Synthesis, Antimalarial Activity, and Preclinical Pharmacology of a Novel Series of 4′-Fluoro and 4′-Chloro Analogues of Amodiaquine. Identification of a Suitable “Back-Up” Compound for N-tert-Butyl Isoquine.
المؤلفون:	Paul M. O’Neill, Alison E. Shone, Deborah Stanford, Gemma Nixon, Eghbaleh Asadollahy, B. Kevin Park, James L. Maggs, Phil Roberts, Paul A. Stocks, Giancarlo Biagini, Patrick G. Bray, Jill Davies, Neil Berry, Charlotte Hall, Karen Rimmer, Peter A. Winstanley, Stephen Hindley, Ramesh B. Bambal, Charles B. Davis, Martin Bates
المصدر:	Journal of Medicinal Chemistry; Apr2009, Vol. 52 Issue 7, p1828-1844, 17p
قاعدة البيانات:	Supplemental Index

الوصف
تدمد:	00222623
DOI:	10.1021/jm8012757