Molecular-Genetic and Epidemiologic Examination of Personnel Subjected to Occupational Irradiation

التفاصيل البيبلوغرافية
العنوان: Molecular-Genetic and Epidemiologic Examination of Personnel Subjected to Occupational Irradiation
المؤلفون: Korzeneva, I., Malinina, T., Afanasyev, K., Rubtsova, G., Veiko, N., Amosenko, F., Osipov, A., Dubrova, Y., Skorodumova, E., Lobacheva, S., Zhuravleva, V., Malysheva, G., Volkova, I., Shishova, R., Sherbakova, I.
المصدر: Radioprotection; January 2008, Vol. 43 Issue: 5
مستخلص: It is given an evaluation of the genetic polymorphisms (Hp, Tf, Gc; 6-PGD, EsD, ACP, PGM1, microsatellite loci CSF1PO и F13AO1, detoxicating genes GSTT1, GSTM1 and GSTP1), individual radiosensitivity (by the criterion of ribosome gene fragments) and DNA-damage rate (Comet-assay) in two cohorts comprised by VNIIEF personnel subjected chronically to gamma-neutron ionizing radiation and to β-radiation of Tritium in comparison with the effects in non-irradiated cohort. There are discussed data on the influence of the occupational irradiation, age and genotype on the rate of structural genome damage, as well as on the activity of the human repair system activity and health status.
قاعدة البيانات: Supplemental Index
الوصف
تدمد:00338451
1769700X
DOI:10.1051/radiopro:2008714