دورية
α-Toxin-permeabilised rabbit fetal ductus arteriosus is more sensitive to Ca2+ than aorta or main pulmonary artery
العنوان: | α-Toxin-permeabilised rabbit fetal ductus arteriosus is more sensitive to Ca2+ than aorta or main pulmonary artery |
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المؤلفون: | Crichton, Catherine A., Smith, Gordon C.S., Smith, Godfrey L. |
المصدر: | Cardiovascular Research; January 1997, Vol. 33 Issue: 1 p223-229, 7p |
مستخلص: | Objectives: The Ca2+ sensitivity of contractile protein-generated tension production was measured in the smooth muscle of the rabbit ductus arteriosus and compared with two neighbouring fetal blood vessels (main pulmonary artery and aorta). The effect of prostaglandin E2 (PGE2), 3-isobutyl-1-methylxanthine (IBMX, a phosphodiesterase inhibitor), cyclic adenosine 3,5-monophosphate (CAMP) and forskolin (an activator of adenylate cyclase) on Ca2+-activated force generated by preparations from ductus arteriosus was also examined. Methods: Strips of smooth muscle from the three vessels were permeabilised using crude ![]() |
قاعدة البيانات: | Supplemental Index |
تدمد: | 00086363 17553245 |
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DOI: | 10.1016/S0008-6363(96)00171-X |