Cloning, expression analysis and chromosomal localization of the human nuclear receptor gene GCNF

التفاصيل البيبلوغرافية
العنوان: Cloning, expression analysis and chromosomal localization of the human nuclear receptor gene GCNF
المؤلفون: Agoulnik, I.Y, Cho, Y, Niederberger, C, Kieback, D.G, Cooney, A.J
المصدر: FEBS Letters; January 1998, Vol. 424 Issue: 1 p73-78, 6p
مستخلص: Germ cell nuclear factor (GCNF) is an orphan member of the nuclear receptor gene superfamily. We report the cloning of a cDNA encoding a new variant of human GCNF from human testis and its expression analysis. Southern blot analysis of the human genomic DNA indicates that the GCNF gene is not closely related to other members within the nuclear receptor superfamily. Chromosomal localization of the GCNF gene shows that the gene is located on chromosome 9 at the locus q33–34.1. In situ hybridization analysis of GCNF expression in the testis shows that human GCNF is expressed exclusively in germ cells.
قاعدة البيانات: Supplemental Index
الوصف
تدمد:00145793
DOI:10.1016/S0014-5793(98)00142-2