دورية
Study of serumHelicobacter pylorisoluble antigen
| العنوان: | Study of serumHelicobacter pylorisoluble antigen |
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| المؤلفون: | Qin-dong, Wu, Yong-liang, Zhu |
| المصدر: | Journal of Zhejiang University - Science A; September 2002, Vol. 3 Issue: 4 p484-488, 5p |
| مستخلص: | Objective: to explore a new serological method for detectingHelicobacter pylori (H. pylori)infection. Methods: Serum soluble antigen ofH. pyloriwas detected by using avidin-biotin ELISA technique to evaluate the status ofH. pyloriinfection and for comparison with rapid urease test (RUT), histologic examination and serology. Results: The sensitivity, specificity, positive predictive value and negative predictive value were 77.46%, 91.07%, 91.67% and 76.12%, respectively. The prevalence rate of serumH. pylorisoluble antigen in 138 patients undergoing endoscopy was similar to the rate obtained by14C-UBT methods (P>0.05). Conclusions: The detection of serumH. pylorisoluble antigen(HpSAg) could be used as a new serological method which is accurate, and convenient, not affected by the memorizing reaction of serum antibody; is more sensitive, more specific and suitable for clinical diagnosis, and evaluation of eradication and for follow-up ofH. pylorias well as for detection in children and pregnant women. |
| قاعدة البيانات: | Supplemental Index |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1673565X 18621775 |
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| DOI: | 10.1007/BF02839495 |