التفاصيل البيبلوغرافية
| العنوان: |
Procalcitonin-guided decision making for duration of antibiotic therapy in neonates with suspected early-onset sepsis: a multicentre, randomised controlled trial (NeoPIns) |
| المؤلفون: |
Stocker, Martin, van Herk, Wendy, el Helou, Salhab, Dutta, Sourabh, Fontana, Matteo S, Schuerman, Frank A B A, van den Tooren-de Groot, Rita K, Wieringa, Jantien W, Janota, Jan, van der Meer-Kappelle, Laura H, Moonen, Rob, Sie, Sintha D, de Vries, Esther, Donker, Albertine E, Zimmerman, Urs, Schlapbach, Luregn J, de Mol, Amerik C, Hoffman-Haringsma, Angelique, Roy, Madan, Tomaske, Maren, Kornelisse, René F, van Gijsel, Juliette, Visser, Eline G, Willemsen, Sten P, van Rossum, Annemarie M C, Bakry, A, Dutta, S, el Helou, S, Kalaniti, K, Pogorzelski, D, Alliston, S, Roy, M, Grey, V, Hauff, K, Hill, S, Kittanakom, S, Janota, J, Visnovska, M, Fontana, M, Lanz, N, Stocker, M, Glauser, D, Zimmerman, U, Tomaske, M, Nelle, M, Schlapbach, LJ, Schuerman, FABA, Sie, SD, van Weissenbruch, MM, van den Dungen, FAM, Strik, M, van den Tooren-de, HK, van Rossum, Groot A, Batstra, M, van der Meer-Kappelle, LH, de Vries, E, de Mol, AC, Bolt-Wieringa, J, Stok, Daniel, Moonen, R, Donker, S, van Gijsel, J, Gondriet, IPE, van Herk, W, Hoekstein, S, Hofhuis, M, Hop, W, de Ligt, L, Manai, B, Kornelisse, R, de Rijke, Y, van Rossum, A, Siiskonen, S, van der Velden, J, Visser, EG, van Wijk, J Asch, Willemsen, S, van der Geijn, GJ, Haringsma, A, Andriessen, PA, Broeren, MAC, Donker, A |
| المصدر: |
The Lancet; August-September 2017, Vol. 390 Issue: 10097 p871-881, 11p |
| مستخلص: |
Up to 7% of term and late-preterm neonates in high-income countries receive antibiotics during the first 3 days of life because of suspected early-onset sepsis. The prevalence of culture-proven early-onset sepsis is 0·1% or less in high-income countries, suggesting substantial overtreatment. We assess whether procalcitonin-guided decision making for suspected early-onset sepsis can safely reduce the duration of antibiotic treatment. |
| قاعدة البيانات: |
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