التفاصيل البيبلوغرافية
العنوان: |
Quantitative analysis of hemin-induced neutrophil extracellular trap formation and effects of hydrogen peroxide on this phenomenon |
المؤلفون: |
Ohbuchi, Ayako, Kono, Mari, Kitagawa, Kaihei, Takenokuchi, Mariko, Imoto, Shion, Saigo, Katsuyasu |
المصدر: |
Biochemistry and Biophysics Reports; September 2017, Vol. 11 Issue: 1 p147-153, 7p |
مستخلص: |
Formation of neutrophil extracellular traps (NETs) can perpetuate sterile inflammation; thus, it is important to clarify their pathophysiological characteristics. Free heme, derived via hemolysis, is a major contributor to organ damage, and reportedly induces neutrophil activation as well as reactive oxygen species (ROS) production and NET formation. For this study, we examined hemin (Fe3+-protoporphyrin IX)-induced NET formation quantitatively in vitro as well as the effects of oxidative stress. |
قاعدة البيانات: |
Supplemental Index |