التفاصيل البيبلوغرافية
| العنوان: |
Quantitative analysis of hemin-induced neutrophil extracellular trap formation and effects of hydrogen peroxide on this phenomenon |
| المؤلفون: |
Ohbuchi, Ayako, Kono, Mari, Kitagawa, Kaihei, Takenokuchi, Mariko, Imoto, Shion, Saigo, Katsuyasu |
| المصدر: |
Biochemistry and Biophysics Reports; September 2017, Vol. 11 Issue: 1 p147-153, 7p |
| مستخلص: |
Formation of neutrophil extracellular traps (NETs) can perpetuate sterile inflammation; thus, it is important to clarify their pathophysiological characteristics. Free heme, derived via hemolysis, is a major contributor to organ damage, and reportedly induces neutrophil activation as well as reactive oxygen species (ROS) production and NET formation. For this study, we examined hemin (Fe3+-protoporphyrin IX)-induced NET formation quantitatively in vitro as well as the effects of oxidative stress. |
| قاعدة البيانات: |
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