P242 The prognosis of patients diagnosed with pulmonary adenocarcinoma at local anaesthetic thoracoscopy (lat): the role of primary t stage

التفاصيل البيبلوغرافية
العنوان: P242 The prognosis of patients diagnosed with pulmonary adenocarcinoma at local anaesthetic thoracoscopy (lat): the role of primary t stage
المؤلفون: Khan, F, Panchal, RK, Richards, C, Ahmed, S, Bennett, J, Tufail, M
المصدر: Thorax; 2017, Vol. 72 Issue: Supplement 3 pA215-A215, 1p
مستخلص: BackgroundAdenocarcinoma is the commonest type of lung cancer and may present with metastatic malignant pleural effusion (MPE)1We observed that some patients with pulmonary adenocarcinoma diagnosed at LAT did not have radiological evidence of primary lung parenchymal lesion. We hypothesised that these patients may have a better prognosis than those with lung nodules or masses due to reduced tumour burden.MethodsWe retrospectively reviewed all patients who underwent LAT from 2006–2016 and screened those diagnosed with pulmonary adenocarcinoma. We reviewed these patients’ radiology, age, gender, TNM staging and prognosis.Results491 patients underwent LAT from 2006–2016. 69/491 (14.05%) were diagnosed with pulmonary adenocarcinoma on histology of parietal pleura. 8 patients out of 69 (3 females, 5 males; mean age 68.25 years) did not have any radiologically detectable lung parenchymal lesion. The TNM staging (7th edition) of these eight patients without lung parenchymal lesion was T0N0M1a, T0N2M1a, T0N2M1a, T0N3M1a, T0N3M1a, T0N0M1b, T0N1M1b, T0N2M1b. Overall prognosis of MPE with lung parenchymal lesion was 331.7+/-63.14 days and without lung parenchymal lesion was 143.5 +/– 32.8 days, p=0.31 (figure 1)[Figure]ConclusionWe have demonstrated no significant difference in the prognosis of patients with MPE secondary to pulmonary adenocarcinoma in the absence or presence of a radiologically determined primary lung parenchymal lesion. Although not statistically different (p=0.31) those patients without a primary lung parenchymal lesion may have a worse prognosis and this requires further investigation in larger cohorts as this may prove to be an important prognostic factor for MPE.ReferenceKasapoglu US, Arinc S, Gungor S, Irmak I, Guney P, Aksoy F, Bandak D, Hazar A. Prognostic factors affecting survival in non-small cell lung carcinoma patients with malignant pleural effusions. The Clinical Respiratory Journal2016;10:791–799.
قاعدة البيانات: Supplemental Index
الوصف
تدمد:00406376
14683296
DOI:10.1136/thoraxjnl-2017-210983.384