دورية
Triterpenoid Saponins from the Seeds of Aesculus chinensisand Their Cytotoxicities
| العنوان: | Triterpenoid Saponins from the Seeds of Aesculus chinensisand Their Cytotoxicities |
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| المؤلفون: | Cheng, Jin-Tang, Chen, Shi-Tao, Guo, Cong, Jiao, Meng-Jiao, Cui, Wen-Jin, Wang, Shu-Hui, Deng, Zhe, Chen, Chang, Chen, Sha, Zhang, Jun, Liu, An |
| المصدر: | Natural Products and Bioprospecting; February 2018, Vol. 8 Issue: 1 p47-56, 10p |
| مستخلص: | Six new triterpenoid saponins, aesculusosides A–F (1–6), together with 19 known ones, were isolated from the seeds of Aesculus chinensis. The new structures were elucidated through extensive spectroscopic analyses and by comparison with previously reported data. Some of the isolates were evaluated for their cytotoxic activities against MCF-7 cell line by an MTT assay, and compounds 15, 16, 19, and 23–25exhibited inhibitory activities against MCF-7 with IC50values ranging from 7.1 to 31.3 μM. |
| قاعدة البيانات: | Supplemental Index |
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Full Text Finder | تدمد: | 21922195 21922209 |
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| DOI: | 10.1007/s13659-017-0148-4 |