دورية
SECRETIN-LIKE ACTIVITY IN SUBCELLULAR FRACTIONS OF CHICKEN INTESTINAL MUCOSA
| العنوان: | SECRETIN-LIKE ACTIVITY IN SUBCELLULAR FRACTIONS OF CHICKEN INTESTINAL MUCOSA |
|---|---|
| المؤلفون: | FIDDES, I. J. S., TROTMAN, C. N. A. |
| المصدر: | Journal of Endocrinology; October 1974, Vol. 63 Issue: 1 p239-245, 7p |
| مستخلص: | Differential centrifugation of chicken intestinal mucosal homogenates showed that particles containing a material with secretin-like activity can be sedimented. The activity appeared to be contained in structures smaller than mitochondria. Approximately 70% of the stimulatory effect of the whole homogenate was sedimented in 10 min at 15000 g. The secretin-like material was released from the particles by treatment with hydrochloric acid and partially purified by heat denaturation of large proteins at pH 3. The relationship between relative dose of mucosal extract and secretory response in the anaesthetized cat was slightly different from that of porcine secretin. |
| قاعدة البيانات: | Supplemental Index |
| تدمد: | 00220795 14796805 |
|---|---|
| DOI: | 10.1677/joe.0.0630239 |