A limited role for DJ1in Parkinson disease susceptibility

التفاصيل البيبلوغرافية
العنوان: A limited role for DJ1in Parkinson disease susceptibility
المؤلفون: Maraganore, D M., Wilkes, K, Lesnick, T G., Strain, K J., de Andrade, M, Rocca, W A., Bower, J H., Ahlskog, J E., Lincoln, S, Farrer, M J.
المصدر: Neurology (Ovid); August 2004, Vol. 63 Issue: 3 p550-553, 4p
مستخلص: An association study of four common polymorphisms in the DJ1gene and Parkinson disease (PD) was conducted. PD probands were compared with their unaffected siblings matched by gender and closest age at study (416 vs 416) and with unrelated control subjects (691 vs 190). None of the four haplotype tagging single-nucleotide polymorphisms (SNPs) was associated with PD overall, but SNP1 (position 4,345 bp) and SNP3 (position 16,491 bp) were associated with PD in women (p0.03 and p0.002).
قاعدة البيانات: Supplemental Index
الوصف
تدمد:00283878
1526632X
DOI:10.1212/01.WNL.0000133402.78621.AD