Serum and tissue tocopherol in sheep after intramuscular injection and(or) dietary vitamin E supplementation

التفاصيل البيبلوغرافية
العنوان: Serum and tissue tocopherol in sheep after intramuscular injection and(or) dietary vitamin E supplementation
المؤلفون: Njeru, C. A., McDowell, L. R., Wilkinson, N. S., Linda, S. B., Rojas, L. X., Williams, S. N.
المصدر: Journal of Animal Science; March 1994, Vol. 72 Issue: 3 p739-745, 7p
مستخلص: In a 28-d trial, 35 wethers weighing 35 to 60 kg were used to evaluate serum, liver, pancreas, kidney, diaphragm, heart, and neck muscle α-tocopherol concentrations after vitamin E administration as i.m. injections and(or) oral supplementation. Treatments (T) were as follows: 1) i.m. DL-α-tocopherol(DL-α-ol) d 1, 2) i.m. DL-α-tocopheryl acetate(DL-α-ac) d 1, 3) i.m. DL-α-ol d 1, 7, 14, and 21, 4) T 1 and oral supplementation, 5) T 3 and oral supplementation, 6) oral supplementation, and 7) control, no E supplementation. Supplemented wethers received 500 IU via injection and(or) 30 IU/kg of diet (acetate form). In a second 10-d trial, blood was periodically collected from 20 wethers weighing 32 to 47 kg that had been assigned to T as follows: 1) control, 2) i.m. DL-α-ol d 1, 3) i.m. DL-α-ac d 1, 4) T 2 d 1 and 7, and 5) T 3 d 1 and 7. Results from repeated measures ANOVA in both trials indicated that there were day × T effects (P< .0001) on serum α-tocopherol. Pretreatment serum tocopherol concentrations were .58 and .66 μg/mL for Trials 1 and 2, respectively. In Trial 1, wethers receiving the four alcohol vitamin E forms showed a rapid increase in serum tocopherol between d 1 and 3, followed by a rapid decline to pretreatment concentrations for T 1, whereas T 3, 4, and 5 maintained higher than pretreatment concentrations after the decline.(ABSTRACT TRUNCATED AT 250 WORDS)
قاعدة البيانات: Supplemental Index
الوصف
تدمد:00218812
15253163
DOI:10.2527/1994.723739x