دورية
Immediate Interferon Gamma Induction Determines Murine Host Compatibility Differences between Toxoplasma gondiiand Neospora caninum
| العنوان: | Immediate Interferon Gamma Induction Determines Murine Host Compatibility Differences between Toxoplasma gondiiand Neospora caninum |
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| المؤلفون: | Coombs, Rachel S., Blank, Matthew L., English, Elizabeth D., Adomako-Ankomah, Yaw, Urama, Ifeanyi-Chukwu Samuel, Martin, Andrew T., Yarovinsky, Felix, Boyle, Jon P. |
| المصدر: | Infection and Immunity; March 2020, Vol. 88 Issue: 4 |
| مستخلص: | Rodents are critical for the transmission of Toxoplasma gondiito the definitive feline host via predation, and this relationship has been extensively studied as a model for immune responses to parasites. Neospora caninumis a closely related coccidian parasite of ruminants and canines but is not naturally transmitted by rodents. We compared mouse innate immune responses to N. caninumand T. gondiiand found marked differences in cytokine levels and parasite growth kinetics during the first 24?h postinfection (hpi). |
| قاعدة البيانات: | Supplemental Index |
| تدمد: | 00199567 10985522 |
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| DOI: | 10.1128/IAI.00027-20 |