دورية
SARS-CoV-2 Infection During Induction Chemotherapy in a Child With High-risk T-Cell Acute Lymphoblastic Leukemia (T-ALL)
| العنوان: | SARS-CoV-2 Infection During Induction Chemotherapy in a Child With High-risk T-Cell Acute Lymphoblastic Leukemia (T-ALL) |
|---|---|
| المؤلفون: | Dantonello, Tobias M., Kartal-Kaess, Mutlu, Aebi, Christoph, Suter-Riniker, Franziska, Busch, Jasmin D., Kubetzko, Susanne, Bourquin, Jean-Pierre, Roessler, Jochen |
| المصدر: | Journal of Pediatric Hematology / Oncology; 20240101, Issue: Preprints |
| مستخلص: | The clinical course of SARS-CoV-2 infection (COVID-19) in children with hematologic malignancies is unclear. We describe the diagnosis, treatment and outcome of a 4-year-old boy with high-risk acute lymphoblastic leukemia and COVID-19. Regardless of immunosuppressive induction chemotherapy his symptoms remained moderate. He received only supportive treatment. Seroconversion occurred in a similar period as in immunocompetent adults. Despite prolonged myelosuppression he did neither acquire secondary infections nor did the treatment delay caused by the infection have a measurable negative impact on the residual disease of acute lymphoblastic leukemia. Intriguingly, residual leukemia even decreased even though he did not receive any antileukemic therapy. |
| قاعدة البيانات: | Supplemental Index |
Full Text Finder | تدمد: | 10774114 15363678 |
|---|---|
| DOI: | 10.1097/MPH.0000000000001943 |