Application of Single Cell Approaches to Study MPN biology

التفاصيل البيبلوغرافية
العنوان: Application of Single Cell Approaches to Study MPN biology
المؤلفون: Royston, Daniel, Mead, Adam J., Psaila, Beth
المصدر: Hematology/Oncology Clinics of North America; 20210101, Issue: Preprints
مستخلص: Philadelphia negative myeloproliferative neoplasms (MPN) are an excellent tractable disease model of a number of aspects of human cancer biology, including genetic evolution, tissue associated fibrosis and cancer stem cells. In this review we discuss recent insights into MPN biology gained from the application of a number of new single cell technologies to study human disease, with a specific focus on single cell genomics, single cell transcriptomics and digital pathology.
قاعدة البيانات: Supplemental Index
الوصف
تدمد:08898588
DOI:10.1016/j.hoc.2021.01.002