دورية
Characterization of sarcomeric myosin heavy chain genes.
| العنوان: | Characterization of sarcomeric myosin heavy chain genes. |
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| المؤلفون: | Wydro, R M, Nguyen, H T, Gubits, R M, Nadal-Ginard, B |
| المصدر: | Journal of Biological Chemistry; January 1983, Vol. 258 Issue: 1 p670-678, 9p |
| مستخلص: | Myosin heavy chain is encoded by a large multigene family. Using pMHC-25, a recombinant cDNA clone isolated from the rat myogenic cell line L6E9, four members of this family in the rat have been isolated and shown to be tissue-specific and developmentally regulated. The coding regions of these genes share regions of homology interspaced with regions of non-homology. Detailed analysis of one embryonic and one adult myosin heavy chain gene shows that the coding sequences are interrupted by numerous intervening sequences whose number, size, and distribution do not appear to be conserved in the same organism or between species. |
| قاعدة البيانات: | Supplemental Index |
| تدمد: | 00219258 1083351X |
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| DOI: | 10.1016/S0021-9258(18)33307-6 |