دورية
A novel CXCR4 antagonist counteracts paradoxical generation of cisplatin-induced pro-metastatic niches in lung cancer
| العنوان: | A novel CXCR4 antagonist counteracts paradoxical generation of cisplatin-induced pro-metastatic niches in lung cancer |
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| المؤلفون: | Bertolini, Giulia, Cancila, Valeria, Milione, Massimo, Lo Russo, Giuseppe, Fortunato, Orazio, Zaffaroni, Nadia, Tortoreto, Monica, Centonze, Giovanni, Chiodoni, Claudia, Facchinetti, Federica, Pollaci, Giuliana, Taiè, Giulia, Giovinazzo, Francesca, Moro, Massimo, Camisaschi, Chiara, De Toma, Alessandro, D’Alterio, Crescenzo, Pastorino, Ugo, Tripodo, Claudio, Scala, Stefania, Sozzi, Gabriella, Roz, Luca |
| المصدر: | Molecular Therapy; October 2021, Vol. 29 Issue: 10 p2963-2978, 16p |
| مستخلص: | Platinum-based chemotherapy remains widely used in advanced non-small cell lung cancer (NSCLC) despite experimental evidence of its potential to induce long-term detrimental effects, including the promotion of pro-metastatic microenvironments. In this study, we investigated the interconnected pathways underlying the promotion of cisplatin-induced metastases. |
| قاعدة البيانات: | Supplemental Index |
| تدمد: | 15250016 15250024 |
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| DOI: | 10.1016/j.ymthe.2021.05.014 |