التفاصيل البيبلوغرافية
العنوان: |
The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparumparasite resistance |
المؤلفون: |
Murithi, James M., Pascal, Cécile, Bath, Jade, Boulenc, Xavier, Gnädig, Nina F., Pasaje, Charisse Flerida A., Rubiano, Kelly, Yeo, Tomas, Mok, Sachel, Klieber, Sylvie, Desert, Paul, Jiménez-Díaz, María Belén, Marfurt, Jutta, Rouillier, Mélanie, Cherkaoui-Rbati, Mohammed H., Gobeau, Nathalie, Wittlin, Sergio, Uhlemann, Anne-Catrin, Price, Ric N., Wirjanata, Grennady, Noviyanti, Rintis, Tumwebaze, Patrick, Cooper, Roland A., Rosenthal, Philip J., Sanz, Laura M., Gamo, Francisco Javier, Joseph, Jayan, Singh, Shivendra, Bashyam, Sridevi, Augereau, Jean Michel, Giraud, Elie, Bozec, Tanguy, Vermat, Thierry, Tuffal, Gilles, Guillon, Jean-Michel, Menegotto, Jérôme, Sallé, Laurent, Louit, Guillaume, Cabanis, Marie-José, Nicolas, Marie Françoise, Doubovetzky, Michel, Merino, Rita, Bessila, Nadir, Angulo-Barturen, Iñigo, Baud, Delphine, Bebrevska, Lidiya, Escudié, Fanny, Niles, Jacquin C., Blasco, Benjamin, Campbell, Simon, Courtemanche, Gilles, Fraisse, Laurent, Pellet, Alain, Fidock, David A., Leroy, Didier |
المصدر: |
Science Translational Medicine; July 2021, Vol. 13 Issue: 603 peabg6013 |
مستخلص: |
We report an acylguanidine preclinical candidate with pharmacological features compatible with single low-dose malaria cure. |
قاعدة البيانات: |
Supplemental Index |