DDX3X structural analysis: Implications in the pharmacology and innate immunity

التفاصيل البيبلوغرافية
العنوان: DDX3X structural analysis: Implications in the pharmacology and innate immunity
المؤلفون: De Colibus, Luigi, Stunnenberg, Melissa, Geijtenbeek, Teunis B.H.
المصدر: Current Research in Immunology; January 2022, Vol. 3 Issue: 1 p100-109, 10p
مستخلص: The human DEAD-Box Helicase 3 X-Linked (DDX3X) is an ATP-dependent RNA helicase involved in virtually every step of RNA metabolism, ranging from transcription regulation in the nucleus to translation initiation and stress granule (SG) formation, and plays crucial roles in innate immunity, as well as tumorigenesis and viral infections.
قاعدة البيانات: Supplemental Index
الوصف
تدمد:25902555
DOI:10.1016/j.crimmu.2022.05.002