Cytotoxic Triterpenoids from Acridocarpus vivy from the Madagascar Rain Forest¹

التفاصيل البيبلوغرافية
العنوان:	Cytotoxic Triterpenoids from Acridocarpus vivy from the Madagascar Rain Forest¹
المؤلفون:	Cao, S., Guza, R. C., Miller, J. S., Andriantsiferana, R., Rasamison, V. E., Kingston, D. G. I.
المصدر:	Journal of Natural Products; June 2004, Vol. 67 Issue: 6 p986-989, 4p
مستخلص:	Bioassay-guided fractionation of the cytotoxic MeOH extract obtained from Acridocarpus vivy led to the isolation of five new triterpenoids, acridocarpusic acids A−E (1−5); three known triterpenoids, moronic acid (6), ursolic acid, and oleanolic acid; and two known flavonoids, 4,5-dihydroxy-7-methoxyflavone and 4,5-dihydroxy-3,7-dimethoxyflavone. The structures of the new compounds 1−5 were established on the basis of extensive 1D and 2D NMR spectroscopic data interpretation. Compound 3 showed significant cytotoxic activity in the A2780 assay, with an IC50 value of 0.7 μg/mL.
قاعدة البيانات:	Supplemental Index

الوصف
تدمد:	01633864 15206025

Cytotoxic Triterpenoids from Acridocarpus vivy from the Madagascar Rain Forest1