دورية
Study on the effect of pH on the biosynthesis of silver nanoparticles using Capparis mooniifruit extract: their applications in anticancer activity, biocompatibility and photocatalytic degradation
| العنوان: | Study on the effect of pH on the biosynthesis of silver nanoparticles using Capparis mooniifruit extract: their applications in anticancer activity, biocompatibility and photocatalytic degradation |
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| المؤلفون: | Anigol, Lakkappa B., Sajjan, Vinodkumar P., Gurubasavaraj, Prabhuodeyara M., Ganachari, Sharanabasava V., Patil, Dhanashree |
| المصدر: | Chemical Papers; 20230101, Issue: Preprints p1-19, 19p |
| مستخلص: | Green synthesis of silver nanoparticles has been studied using a variety of plant extracts for biomedical applications in cancer nanomedicine. Silver nanoparticles were synthesized using Capparis Moonii (CM) fruit extract as reducing agent. Intense surface plasmon resonance (SPR) absorption peaks at 404–420 nm in the UV–visible spectrum appeared to indicate the formation of AgNPs. The function of Capparis Mooniifruit extract as a reducing and capping agent was confirmed by Fourier transform infrared spectroscopy (FTIR). The morphology of the produced nanoparticles was determined using scanning electron microscopy and they exhibit a spherical shape with a size range of 10–20 nm, according to high-resolution transmission electron microscopy. Energy-dispersive X-ray analysis (EDX) demonstrated that silver is present in the silver nanoparticles at a percentage of 56.91% by atom. To determine the surface charge of AgNPs formed during biosynthesis, the zeta potential measurement was carried out. The lack of cytotoxicity to blood erythrocytes and normal human fibroblasts cell lines confirms the blood biocompatibility and cell compatibility of the synthesized AgNPs. The synthesized AgNPs are cytotoxic to breast cancer (MCF-7), lung cancer (A549), pancreatic cancer (PANC-1) and skin cancer (A431) cell lines with IC50values of 12.06, 24.87, 26.49 and 84.57 µg/mL, respectively. The synthesized silver nanoparticles show excellent photocatalytic activity on the degradation of rose bengal (RB) and methylene blue (MB). By observing the breakdown of RB and MB under direct sunlight radiation, the photocatalytic activity of the synthesized AgNPs was evaluated. At pH-2, 100% photocatalytic degradation of RB was completed in 60 min, whereas at pH-8, 96% photocatalytic degradation of MB was completed in 240 min. |
| قاعدة البيانات: | Supplemental Index |
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Full Text Finder | تدمد: | 25857290 13369075 |
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| DOI: | 10.1007/s11696-023-02707-5 |