دورية
Pembrolizumab-Induced Nodular Posterior Scleritis
| العنوان: | Pembrolizumab-Induced Nodular Posterior Scleritis |
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| المؤلفون: | McNelly, Calvin L., Haider, Asghar A., Wann, Robert C., Crosson, Jason N., Mason, John O. |
| المصدر: | Journal of VitreoRetinal Diseases; July 2023, Vol. 7 Issue: 4 p348-351, 4p |
| مستخلص: | Purpose:To report a case of painless posterior scleritis presenting as a choroidal nodule in a patient with history of a tumor being treated with pembrolizumab. Methods:A case and its findings were analyzed, and a relevant literature review was performed. Results: A 20-year-old woman with a history of ependymoma presented with painless blurred vision in the right eye after being started on pembrolizumab for a tumor recurrence. Fundoscopy showed a solitary amelanotic choroidal lesion with surrounding subretinal fluid in the affected eye. Ultrasonography showed moderate internal reflectivity and fluid in Tenon capsule consistent with nodular posterior scleritis. After a course of systemic steroids and discontinuation of the pembrolizumab, the choroidal lesion completely resolved. Conclusions: Clinicians should be aware of posterior scleritis as an ocular complication of this class of medications. |
| قاعدة البيانات: | Supplemental Index |
Full Text Finder | تدمد: | 24741264 24741272 |
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| DOI: | 10.1177/24741264231163396 |