دورية
Solanum americanumgenome-assisted discovery of immune receptors that detect potato late blight pathogen effectors
| العنوان: | Solanum americanumgenome-assisted discovery of immune receptors that detect potato late blight pathogen effectors |
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| المؤلفون: | Lin, Xiao, Jia, Yuxin, Heal, Robert, Prokchorchik, Maxim, Sindalovskaya, Maria, Olave-Achury, Andrea, Makechemu, Moffat, Fairhead, Sebastian, Noureen, Azka, Heo, Jung, Witek, Kamil, Smoker, Matthew, Taylor, Jodie, Shrestha, Ram-Krishna, Lee, Yoonyoung, Zhang, Chunzhi, Park, Soon Ju, Sohn, Kee Hoon, Huang, Sanwen, Jones, Jonathan D. G. |
| المصدر: | Nature Genetics; 20230101, Issue: Preprints p1-10, 10p |
| مستخلص: | Potato (Solanum tuberosum) and tomato (Solanum lycopersicon) crops suffer severe losses to late blight caused by the oomycete pathogen Phytophthora infestans. Solanum americanum, a relative of potato and tomato, is globally distributed and most accessions are highly blight resistant. We generated high-quality reference genomes of four S. americanumaccessions, resequenced 52 accessions, and defined a pan-NLRome of S. americanumimmune receptor genes. We further screened for variation in recognition of 315P. infestansRXLR effectors in 52 S. americanumaccessions. Using these genomic and phenotypic data, we cloned three NLR-encoding genes, Rpi-amr4, R02860and R04373, that recognize cognate P. infestansRXLR effectors PITG_22825(AVRamr4), PITG_02860and PITG_04373. These genomic resources and methodologies will support efforts to engineer potatoes with durable late blight resistance and can be applied to diseases of other crops. |
| قاعدة البيانات: | Supplemental Index |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 10614036 15461718 |
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| DOI: | 10.1038/s41588-023-01486-9 |