Cancer mortality among a group of fluorspar miners exposed to radon progeny.

التفاصيل البيبلوغرافية
العنوان: Cancer mortality among a group of fluorspar miners exposed to radon progeny.
المؤلفون: Morrison, H I, Semenciw, R M, Mao, Y, Wigle, D T
المصدر: American Journal of Epidemiology; December 1988, Vol. 128 Issue: 6 p1266-1275, 10p
مستخلص: A cohort study of the mortality experience (1950-1984) of 1,772 Newfoundland underground fluorspar miners occupationally exposed to high levels of radon daughters (mean dose = 382.8 working levels months) has been conducted. Observed numbers of cancers of the lung, salivary gland, and buccal cavity and pharynx were significantly elevated among these miners. A highly significant relation was noted between radon daughter exposure and risk of dying of lung cancer; the small numbers of salivary gland (n = 2) and buccal cavity and pharynx (n = 6) cancers precluded meaningful analysis of dose response. Attributable and relative risk coefficients for lung cancer were estimated as 6.3 deaths per working level month per million person-years and 0.9% per working level month, respectively. Relative risk coefficients were highest for those first exposed before age 20 years. Cigarette smokers had relative and attributable risk coefficients comparable to those of nonsmokers. Relative risks fell sharply with age, whereas attributable risks were lowest in the youngest and oldest age groups. The results suggest that efforts to raise existing occupational exposure standards may be inappropriate.
قاعدة البيانات: Supplemental Index
الوصف
تدمد:00029262
14766256
DOI:10.1093/oxfordjournals.aje.a115080