دورية
Fabrication and characterization of polyvinyl alcohol/TiO2membrane immersed in simulated body fluid for biomedical application
| العنوان: | Fabrication and characterization of polyvinyl alcohol/TiO2membrane immersed in simulated body fluid for biomedical application |
|---|---|
| المؤلفون: | Nguyen, Dien Thi My, Huynh, Khanh Do Gia, Nguyen, Thuy Thanh Doan, Huynh, Vu Tan, Nguyen, Phuong Tuyet, Nguyen, Linh Thuy Ba |
| المصدر: | Vietnam Journal of Chemistry; December 2023, Vol. 61 Issue: 6 p741-754, 14p |
| مستخلص: | In this study, we synthesized hydroxyapatite (HA) on polyvinyl alcohol/TiO2(PVA/TiO2) in which TiO2was prepared by the sol‐gel method. HA was formed by immersing the membrane in the simulated body fluid (SBF) solution. We improved the mechanical strength of the membranes by adding glutaraldehyde (GA) combining with heat treatment to cross‐link the polymer network. In addition, the composition of TiO2crystalline phase, TiO2content in each membrane, and the duration of membrane immersion in SBF solution were investigated. The morphological structures of hydroxyapatite/polyvinyl alcohol/TiO2(HA/PVA/TiO2) membranes were characterized by IR, SEM, and XRD. We confirmed that the HA formation depended on the TiO2content and phase composition (rutile or anatase). Membranes containing TiO2rutile‐phase showed more pronounced HA formation than membranes containing TiO2anatase‐phase. The appearance of HA also depended on SBF immersion duration. Membranes soaked for 3 weeks showed significantly more HA formation than membranes soaked for 1 and 2 weeks. Furthermore, the number of cells in membranes soaked for 3 weeks was clearly higher than in other membranes. Finally, HA/PVA/TiO2membranes containing 25 wt.% of TiO2rutile‐phase are biocompatible based on the number of viable cells and thus have the potential for biomedical application. |
| قاعدة البيانات: | Supplemental Index |
| تدمد: | 08667144 25728288 |
|---|---|
| DOI: | 10.1002/vjch.202300015 |