The Klebsiellamannose phosphotransferase system promotes proliferation and the production of extracellular polymeric substances from mannose, facilitating adaptation to the host environment

التفاصيل البيبلوغرافية
العنوان: The Klebsiellamannose phosphotransferase system promotes proliferation and the production of extracellular polymeric substances from mannose, facilitating adaptation to the host environment
المؤلفون: Miki, Suguru, Fukamachi, Haruka, Itsumi, Momoe, Fujiwara, Nagatoshi, Takaki, Takashi, Kurosawa, Mie, Morisaki, Hirobumi, Suzuki, Noriyuki, Kuwata, Hirotaka
المصدر: Journal of Oral Biosciences; March 2024, Vol. 66 Issue: 1 p119-125, 7p
مستخلص: Klebsiellaspp., an opportunistic infectious organism, is commensal in the nasal and oral cavities of humans. Recently, it has been reported that oral Klebsiellaspp. ectopically colonize the intestinal tract and induce the accumulation of intestinal Th1 cells. For oral bacteria to colonize the intestinal tract, they need to compete for nutrients with indigenous intestinal bacteria. Therefore, we focused on mannose, a mucus-derived sugar, and the mannose phosphotransferase system (PTS) (ManXYZ), a mechanism for mannose uptake, in terms of their effects on intestinal colonization and immune responses to Klebsiellaspp.
قاعدة البيانات: Supplemental Index
الوصف
تدمد:13490079
DOI:10.1016/j.job.2024.01.003