The effect of computerised decision support alerts tailored to intensive care on the administration of high-risk drug combinations, and their monitoring: a cluster randomised stepped-wedge trial

التفاصيل البيبلوغرافية
العنوان: The effect of computerised decision support alerts tailored to intensive care on the administration of high-risk drug combinations, and their monitoring: a cluster randomised stepped-wedge trial
المؤلفون: Bakker, Tinka, Klopotowska, Joanna E, Dongelmans, Dave A, Eslami, Saeid, Vermeijden, Wytze J, Hendriks, Stefaan, ten Cate, Julia, Karakus, Attila, Purmer, Ilse M, van Bree, Sjoerd H W, Spronk, Peter E, Hoeksema, Martijn, de Jonge, Evert, de Keizer, Nicolette F, Abu-Hanna, Ameen, van Balen, Dorieke E.M., Schutte, Peter F., Sigtermans, Marnix J., Kuck, Emile M., van Kan, Erik J.M., van der Steen, Marijke S., Bosma, Liesbeth E., Nowitzky, Ralph O., Beishuizen, Albertus, Movig, Kris L.L., Wesselink, Elsbeth M., Lammers, Rick J.W., Lau, Cedric, Masselink, Joost B., Bosman, Rob J., de Lange, Dylan W., van Marum, Rob J., van der Sijs, Heleen, Franssen, Eric J.F., Kieft, Hans, van den Bergh, Walter M., Bult, Wouter, Renes, Maurits H., de Feiter, Peter W., Wils, Evert-Jan, Hunfeld, Nicole G.M., Mulder, Froukje, Duyvendak, Michiel
المصدر: The Lancet; February 2024, Vol. 403 Issue: 10425 p439-449, 11p
مستخلص: Drug–drug interactions (DDIs) can harm patients admitted to the intensive care unit (ICU). Yet, clinical decision support systems (CDSSs) aimed at helping physicians prevent DDIs are plagued by low-yield alerts, causing alert fatigue and compromising patient safety. The aim of this multicentre study was to evaluate the effect of tailoring potential DDI alerts to the ICU setting on the frequency of administered high-risk drug combinations.
قاعدة البيانات: Supplemental Index
الوصف
تدمد:01406736
1474547X
DOI:10.1016/S0140-6736(23)02465-0