Green Synthesis of Silver Nanoparticles Using Petai (Parkia speciosaHassk.) Seed: Characterization, Stability Study, and Antibacterial Activity

التفاصيل البيبلوغرافية
العنوان: Green Synthesis of Silver Nanoparticles Using Petai (Parkia speciosaHassk.) Seed: Characterization, Stability Study, and Antibacterial Activity
المؤلفون: Nanda, Yogie Andika Tri, Santosa, Djoko, Zai, Khadijah
المصدر: Iranian Journal of Science; 20240101, Issue: Preprints p1-13, 13p
مستخلص: Nanoparticles have great potential in medicinal aspects. Among metal nanoparticles, silver nanoparticles (AgNPs) are very popular because of their ability to act in many treatments such as antibacterial, antifungal, antioxidant, anticancer, antidiabetic, and anti-inflammatory. In this study, we synthesized AgNPs by using a safe and non-toxic method (green method) using petai seed extract. Extract can be useful as a reductor and stabilizer agent in the synthesis of AgNPs. The AgNPs were characterized by UV–Vis spectroscopy, zeta sizer, SEM–EDX, TEM, and FTIR. The antibacterial effects of The AgNPs were studied by disk diffusion and microdilution methods against Staphylococcus aureusand Escherichia coli. The UV–Vis spectrum showed a peak at 424 nm, an average particle size of 116.5 ± 1.07 nm with PDI of 0.193 ± 0.01, and a zeta potential of − 13.5 ± 0.2 mV. The SEM–EDX and TEM confirmed that AgNPs have a spherical shape. The FTIR spectra showed a shift in the AgNPs wavelength which confirmed the reduction process. Moreover, the disk diffusion test showed that AgNPs and silver nitrate at a concentration of 5000 µg/mL create inhibition zone of 13.4 ± 3.8 and 11.5 ± 0.5 for S. aureus; 11.9 ± 1.3 and 13.1 ± 1.4 mm for E. coli, respectively. Microdilution test showed that kanamycin, AgNPs, and silver were able to inhibit the growth of S. aureuswith MIC, respectively, of 11.5, 115.6, and 2797.3 µg/mL; and E. coliwith MIC, respectively, of 4.0, 1264.3, and 1771.0 µg/mL. These results suggest that AgNPs can be synthesized by using petai seed and have the ability as an alternative antibacterial agent.
قاعدة البيانات: Supplemental Index
الوصف
تدمد:27318095
27318109
DOI:10.1007/s40995-024-01586-z