دورية
Neopetromin, a Cyclic Tripeptide with a C–N Cross-Link, from the Marine Sponge Neopetrosiasp., That Causes Vacuole Fragmentation in Tobacco BY-2 Cells
| العنوان: | Neopetromin, a Cyclic Tripeptide with a C–N Cross-Link, from the Marine Sponge Neopetrosiasp., That Causes Vacuole Fragmentation in Tobacco BY-2 Cells |
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| المؤلفون: | Hitora, Yuki, El-Desoky, Ahmed H., Sadahiro, Yusaku, Sejiyama, Ai, Kinoshita, Amiri, Ise, Yuji, Angkouw, Esther D., Mangindaan, Remy E. P., Higaki, Takumi, Tsukamoto, Sachiko |
| المصدر: | Journal of Natural Products; 20240101, Issue: Preprints |
| مستخلص: | HPLC-MS analysis revealed the presence of an unreported peptide in the extract of the marine sponge Neopetrosiasp. Its structure was determined as a tripeptide, named neopetromin (1), composed of two tyrosine and one tryptophan residues with a heteroaromatic C–N cross-link between side chains. The absolute configuration of amino acids was determined using Marfey’s method after ozonolysis and hydrolysis of 1. Compound 1promoted vacuole fragmentation in an actin-independent manner in tobacco BY-2 cells. |
| قاعدة البيانات: | Supplemental Index |
Find this issue from the American Chemical Society | تدمد: | 01633864 15206025 |
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| DOI: | 10.1021/acs.jnatprod.4c00158 |