دورية
Lazaroid and Pentoxifylline Suppress Sepsis-Induced Increases in Renal Vascular Resistance via Altered Arachidonic Acid Metabolism
| العنوان: | Lazaroid and Pentoxifylline Suppress Sepsis-Induced Increases in Renal Vascular Resistance via Altered Arachidonic Acid Metabolism |
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| المؤلفون: | Krysztopik, Richard J., Matheson, Paul J., Spain, David A., Garrison, R.Neal, Wilson, Mark A. |
| المصدر: | Journal of Surgical Research; September 2000, Vol. 93 Issue: 1 p75-81, 7p |
| مستخلص: | Early sepsis leads to renal hypoperfusion, despite a hyperdynamic systemic circulation. It is thought that failure of local control of the renal microcirculation leads to hypoperfusion and organ dysfunction. Of the many mediators implicated in the pathogenesis of microvascular vasoconstriction, arachidonic acid metabolites are thought to be important. Vasoconstriction may be due to excess production of vasoconstrictors or loss of vasodilators. |
| قاعدة البيانات: | Supplemental Index |
Full Text Finder | تدمد: | 00224804 10958673 |
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| DOI: | 10.1006/jsre.2000.5947 |